GENOMICS

Our genomics platform is dedicated to uncovering how genetic variations influence the biology of aging. We focus on the intersection between genomic variants and telomere integrity, a critical axis in the onset and progression of age-related diseases.

Telomeres protect chromosome ends and are essential for maintaining genomic stability. Their dysfunction, whether through accelerated shortening, impaired repair, or loss of regulatory control, can lead to cellular senescence and disease. We investigate how both inherited and somatic genetic variants impact key regulators of telomere biology, including telomerase function, shelterin complex components, and DNA damage response pathways.

Our genomic pipeline integrates high-resolution variant analysis with proprietary algorithms to prioritize disease-relevant mutations. By focusing on genes that modulate telomere maintenance, we aim to identify molecular signatures that contribute to biological aging and age-associated disorders.

By linking telomere biology to actionable genomic data, we provide pharmaceutical and biotech partners with the tools to identify new drug targets, stratify patients, and accelerate the development of therapies for age-related diseases. We place particular emphasis on studying underrepresented ethnic groups, whose genomic data remain critically under explored in aging research, to ensure that future medical solutions are inclusive and equitable.